{"id":2275,"date":"2016-01-07T11:55:00","date_gmt":"2016-01-07T03:55:00","guid":{"rendered":"https:\/\/tcr.cph.ntu.edu.31app.tw\/?p=2275"},"modified":"2022-01-25T11:53:54","modified_gmt":"2022-01-25T03:53:54","slug":"%e7%99%8c%e7%99%bb%e7%ac%ac105001%e8%99%9f%e9%80%9a%e7%9f%a5%e6%96%87-%e5%9b%a0%e6%87%89105%e5%b9%b4%e7%99%8c%e7%97%87%e7%99%bb%e8%a8%98%e5%af%a6%e5%8b%99%e4%bd%9c%e6%a5%ad%e4%b9%8b%e9%9c%80","status":"publish","type":"post","link":"https:\/\/twcr.tw\/?p=2275","title":{"rendered":"[\u764c\u767b\u7b2c105001\u865f\u901a\u77e5\u6587] \u56e0\u61c9105\u5e74\u764c\u75c7\u767b\u8a18\u5be6\u52d9\u4f5c\u696d\u4e4b\u9700\u6c42\u53ca100\u5e74\u7248\u53f0\u7063\u764c\u75c7\u767b\u8a18\u6458\u9304\u624b\u518a-104\u5e74\u4fee\u8a02\u7248\u4f7f\u7528\u8aaa\u660e\uff0c\u8acb \u8cb4\u9662\u4f9d\u8aaa\u660e\u6bb5\u8fa6\u7406"},"content":{"rendered":"

\u4e00\u3001\u672c\u6848\u4fc2\u4f9d\u885b\u751f\u798f\u5229\u90e8\u570b\u6c11\u5065\u5eb7\u7f72\u59d4\u8a17\u300c\u53f0\u7063\u764c\u75c7\u767b\u8a18\u5de5\u4f5c\u8a08\u756b\u300d\u8fa6\u7406\u3002<\/p>\n

\u4e8c\u3001\u300c100\u5e74\u7248\u53f0\u7063\u764c\u75c7\u767b\u8a18\u6458\u9304\u624b\u518a\u300d- 104\u5e74\u4fee\u8a02\u7248\u53ca\u300c\u764c\u75c7\u90e8\u4f4d\u7279\u5b9a\u56e0\u5b50\uff08SSF\uff09\u7de8\u78bc\u624b\u518a\u300d- 104\u5e74\u4fee\u8a02\u7248\uff0c\u696d\u7531\u5404\u91ab\u9662\u60e0\u793a\u610f\u898b\u4e26\u4f9d\u64da\u5c08\u5bb6\u6703\u8b70\u8a0e\u8ad6\u5f8c\u4fee\u8a02\u5b8c\u7ae3\uff0c\u4fee\u8a02\u7248\u4e4b\u9644\u9304\u4fee\u8a02\u8655\u6709\u8a73\u7d30\u66f4\u65b0\u8aaa\u660e\uff0c\u63d0\u4f9b\u91ab\u9662\u53c3\u8003\u3002
\n\u5b8c\u6574\u4fee\u8a02\u7248\u6a94\u6848\u8acb\u9015\u81f3\u53f0\u7063\u764c\u75c7\u767b\u8a18\u4e2d\u5fc3\u7db2\u7ad9\u4e0b\u8f09\uff0c\u7db2\u5740\u5982\u4e0b\uff1a
\nhttp:\/\/tcr.cph.ntu.edu.tw\/main.php?Page=A6\u3002<\/p>\n

\u4e09\u3001\u81ea105\u5e74\u8d77\u6240\u6709\u8a3a\u65b7\u5e74\u5ea6\u500b\u6848\uff0c\u5747\u5168\u9762\u63a1\u7528\u4e0a\u8ff0104\u5e74\u4fee\u8a02\u7248\u7533\u5831\u3002\u53e6103\u8a3a\u65b7\u5e74\u4ecd\u9700\u7533\u5831\u500b\u6848\uff0c\u53ef\u6cbf\u7528103\u5e74\u4fee\u8a02\u7248\u672c\u7533\u5831\uff0c\u4f46\u5fc5\u9808\u65bc105\u5e741\u67088\u65e5\u524d\u4f9d\u6cd5\u5b8c\u6210\u7533\u5831\u3002<\/p>\n

\u56db\u3001\u300c100\u5e74\u7248\u53f0\u7063\u764c\u75c7\u767b\u8a18\u6458\u9304\u624b\u518a\u300d\u8207\u300c\u764c\u75c7\u90e8\u4f4d\u7279\u5b9a\u56e0\u5b50\uff08SSF\uff09\u7de8\u78bc\u624b\u518a\u300d-104\u5e74\u4fee\u8a02\u7248\u91cd\u8981\u4fee\u6b63\u6458\u8981\u5982\u4e0b\uff0c\u8a73\u7d30\u5167\u5bb9\u8acb\u53c3\u8003104\u5e74\u4fee\u8a02\u7248\u624b\u518a\uff1a<\/p>\n

    \n
  1. \u539f\u9810\u8a08\u81ea104\u8a3a\u65b7\u5e74\u764c\u75c7\u500b\u6848\uff0c\u65bc\u53f0\u7063\u764c\u75c7\u767b\u8a18\u9577\u8868\u6458\u9304\u624b\u518a\u5176\u4ed6\u56e0\u5b50\u4e2d\u65b0\u589e\u9996\u6b21\u6cbb\u7642\u524d\u751f\u6d3b\u529f\u80fd\u72c0\u614b\u8a55\u4f30(Assessment of Performance Status before Treatment)\u300d\u6b04\u4f4d\uff0c\u6c7a\u8b70\u4e0d\u65b0\u589e<\/strong>\uff0c\u7dad\u6301\u9577\u8868114\u6b04\u4f4d\u8207\u77ed\u886842\u6b04\u4f4d\u3002<\/li>\n
  2. \u76f4\u8178\u4e59\u72c0\u7d50\u8178\u3001\u76f4\u8178\u764cSSF9\u300c\u76f4\u8178\u816b\u7624\u4e0b\u7de3\u8207\u809b\u9580\u53e3\u7684\u8ddd\u96e2\u300d\uff1a\u65b0\u589e\u76f4\u8178\u4e59\u72c0\u7d50\u8178(Rectosigmoid junction\uff0cC199)\u500b\u6848\u70ba\u4e0d\u9069\u7528(\u7de8\u78bc988)\u3002<\/li>\n
  3. \u809d\u764cSSF3\u300cChild Pugh\u5206\u6578\u300d\uff1a\u8868\u683c\u5167\u201dProthrombin time prolonged, sec (INR) \u51dd\u8840\u9176\u539f\u6642\u9593\u201d\u6578\u503c\u7bc4\u570d\u4fee\u6b63\u3002<\/li>\n<\/ol>\n

    \u4e94\u3001\u764c\u75c7\u767b\u8a18\u6458\u9304\u7de8\u78bc\u898f\u5247\u901a\u77e5\uff1a
    \n\u7d93\u764c\u75c7\u767b\u8a18\u5b78\u6703\u6559\u80b2\u59d4\u54e1\u6703\u5171\u8b58\u6c7a\u8b70\uff0c\u56e0UFT\/UFUR\u5c6c\u8907\u5408\u5f0f\u85e5\u7269(Tegafur+Uracil)\uff0cTegafur\u70ba5-FU\u7684\u524d\u9a45\u7269\u8cea(\u5c6c\u5316\u5b78\u85e5\u7269)\uff0cUracil\u70ba\u6838\u9178\u69cb\u6210\u6210\u4efd\uff0c\u4f5c\u7528\u5728\u6291\u5236\u5c075-FU\u4ee3\u8b1d(Uracil\u975e\u5316\u5b78\u85e5\u7269)\uff1b\u6545UFT\/UFUR\u65bc\u300c\u5916\u9662\u5316\u5b78\u6cbb\u7642\u300d\u8207\u300c\u7533\u5831\u91ab\u9662\u5316\u5b78\u6cbb\u7642\u300d\u6b04\u4f4d\u61c9\u767b\u930402\u53ea\u6709\u3127\u7a2e\u5316\u5b78\u85e5\u7269\u3002<\/p>\n

    \u516d\u3001\u8fd1\u5e74WHO\u65b0\u51fa\u7248bluebook\u91cd\u8981\u8a0a\u606f\u6458\u9304\u5982\u4e0b\uff0c\u53e6\u9644\u4ef6<\/a>\u63d0\u4f9b\u65b0\u589eICD-O-3\u7de8\u78bc\u8207\u6558\u8ff0\u4fc2\u4f9d\u64daWHO Classification of Tumours of the Lung, Pleura, Thymus and Heart (2015)\u3001WHO Classification of Tumours of Female Genital Organs (2014)\u3001WHO Classification of Tumours of Soft Tissue and Bone (2013)\u8207WHO Classification of Tumours of the Breast (2012)\u5f59\u6574\u800c\u6210\uff0c\u56e02000\u5e74\u51fa\u7248\u4e4bICD-O-3\u7de8\u78bc\u4e0d\u6577\u4f7f\u7528\uff0c\u4e14\u73fe\u884c\u75c5\u7406\u5831\u544a\u6309\u6700\u65b0\u7d44\u7e54\u578b\u614b\u8a18\u8f09\uff0c\u6545\u63d0\u4f9b\u6700\u65b0\u75c5\u7406\u7d44\u7e54\u578b\u614b\u7de8\u78bc\u4f9b\u91ab\u9662\u4f7f\u7528\u3002(\u9644\u4ef6\u66f4\u65b0\u81ea\u764c\u767b103012\u865f\u901a\u77e5\u6587\u5167\u5bb9)\uff1a<\/p>\n

      \n
    1. \u4f9d\u64da2015\u5e74\u65b0\u51fa\u7248WHO Classification of Tumours of the Lung, Pleura, Thymus and Heart\uff1a\u80f8\u817a\u7624(Thymoma)\u500b\u6848\u82e5\u5c6c\u65bc\u4e0b\u8868\u5167\u4e4b\u7d44\u7e54\u578b\u614b\u8005\uff0c\u81ea104<\/strong>\u8a3a\u65b7\u5e74\u8d77<\/strong>\u8996\u70ba\u60e1\u6027\u816b\u7624\u4e14\u4f9d\u898f\u5b9a\u7de8\u78bc\u7533\u5831\u3002<\/li>\n<\/ol>\n\n\n\n\n\n\n\n\n\n\n
      \u75c5\u7406\u5831\u544a\u63cf\u8ff0<\/td>\nICD-O-3 MOCDE<\/td>\n<\/tr>\n
      Type A thymoma, including atypical variant<\/td>\n8581\/3<\/td>\n<\/tr>\n
      Type AB thymoma<\/td>\n8582\/3<\/td>\n<\/tr>\n
      Type B1 thymoma<\/td>\n8583\/3<\/td>\n<\/tr>\n
      Type B2 thymoma<\/td>\n8584\/3<\/td>\n<\/tr>\n
      Type B3 thymoma<\/td>\n8585\/3<\/td>\n<\/tr>\n
      Metaplastic thymoma<\/td>\n8580\/3<\/td>\n<\/tr>\n
      Sclerosing thymoma<\/td>\n8580\/3<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
        \n
      1. 2015\u5e74\u65b0\u51fa\u7248WHO Classification of Tumours of the Lung, Pleura, Thymus and Heart\uff1a\u539f\u672cbluebook\u7de8\u78bc\u70ba8250\/2-Minimally invasive adenocarcinoma, Non-mucinous\uff0c\u82078410\/2-Adenocarcinoma in situ, Non-mucinous\uff0c\u7d93\u7531\u53f0\u7063\u75c5\u7406\u5b78\u6703\u5411WHO\u8a62\u554f\u5f8c\u78ba\u8a8d\u7d19\u672c\u70ba\u8aa4\u690d\uff0c\u6b63\u78ba\u7684\u7de8\u78bc\u70ba8256\/3-Minimally invasive adenocarcinoma, Non-mucinous\uff0c\u82078250\/2-Adenocarcinoma in situ, Non-mucinous\u3002<\/li>\n
      2. \u4f9d\u64da\u4e0a\u8ff0\u7b2c2\u9ede2015\u5e74\u65b0\u51fa\u7248\u7684WHO bluebook\uff1a\u82e5\u80ba\u764c\u7d44\u7e54\u578b\u614b\u70baAcinar adenocarcinoma\uff0c\u8acb\u7de8\u78bc\u70ba8551\/3\u3002<\/li>\n
      3. \u4f9d\u64da2013\u5e74\u51fa\u7248WHO Classification of Tumours of Soft Tissue and Bone\uff1a\u7d44\u7e54\u578b\u614b\u7de8\u78bcDermatofibrosarcoma protuberans (8832\/1)\u8207Pigmented dermatofibrosarcoma protuberans (8833\/1)\uff0c\u5176\u6027\u614b\u78bc\u5df2\u75313(\u60e1\u6027)\u6539\u70ba1(\u4e0d\u78ba\u5b9a\u662f\u5426\u826f\u6027\u6216\u60e1\u6027)\uff0c\u4e0d\u7528\u7533\u5831\uff1b\u82e5\u7d44\u7e54\u578b\u614b\u70baFibrosarcomatous dermatofibrosarcoma protuberans (8832\/3)\uff0c\u5247\u9808\u7533\u5831\u3002<\/li>\n
      4. \u4f9d\u64da2012\u5e74\u51fa\u7248WHO Classification of Tumours of the Breast\uff1a
        \n\u65b0\u589e\u4e73\u764c\u7d44\u7e54\u578b\u614b\u7de8\u78bcEncapsulated papillary carcinoma\u00a0(8504\/2)\u8207Encapsulated papillary carcinoma\u00a0with invasion\u00a0(8504\/3)\uff0c\u56e0ICD-O-3\u81f3\u4eca\u5c1a\u672a\u6539\u7248\uff0c\u539f\u6b64\u985e\u500b\u6848\u50c5\u80fd\u501f\u7528\u7532\u72c0\u817a\u764c\u7d44\u7e54\u578b\u614b\u7de8\u78bcPapillary carcinoma, encapsulated\u00a0(8343\/3)\u4f86\u9032\u884c\u7533\u5831\uff0c\u4f46\u81ea103\u5e74\u7b2c\u56db\u5b63\u8d77\u5373\u53ef\u4f9d\u65b0\u589e\u7de8\u78bc\u7533\u5831\uff1b\u53e6\u8acb\u6ce8\u610f\u6b64\u985e\u578b\u539f\u4f4d\u764c\u8207\u4fb5\u8972\u764c\u7684\u63cf\u8ff0\u5dee\u7570\u3002<\/li>\n<\/ol>\n

        \u4e03\u3001\u795e\u7d93\u5167\u5206\u6ccc\u764c(Neuroendocrine Tumors, NETs)\u5206\u7d1a\u5206\u5316\u767b\u9304\u898f\u5247\uff1a<\/p>\n

        The Pathologic Classification of Neuroendocrine Tumors: A Review of Nomenclature, Grading, and Staging Systems (Pancreas 2010;39:707-12)\u8207AJCC\u7b2c\u4e03\u724817\u7ae0\u7bc0\u5167\u5bb9\uff0c\u4e26\u8aee\u8a62\u75c5\u7406\u5b78\u6703\u5c08\u5bb6\u5f8c\u6574\u7406\u5982\u4e0b\uff1a<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
        <\/td>\nCode<\/strong><\/td>\nLung and Thymus<\/strong><\/td>\nGastroEnteroPancreatic-NETs<\/strong>*<\/td>\n<\/tr>\n
        WHO<\/td>\nENETS, WHO<\/td>\n<\/tr>\n
        Grade<\/strong><\/td>\n<\/tr>\n
        Low grade<\/strong><\/td>\n1<\/strong><\/td>\nCarcinoid tumor 8240\/3<\/td>\nNET Grade 1 (G1) 8240\/3<\/td>\n<\/tr>\n
        Intermediate grade<\/strong><\/td>\n2<\/strong><\/td>\nAtypical carcinoid tumor 8249\/3<\/td>\nNET Grade 2 (G2) 8249\/3<\/td>\n<\/tr>\n
        High grade<\/strong><\/td>\n3<\/strong><\/td>\nSmall cell carcinoma 8041\/3<\/p>\n

        Large cell NEC 8013\/3<\/td>\n

        		NEC Grade 3 (G3), Small cell NEC 8041\/3<\/p>\n

        NEC Grade 3 (G3), Large cell NEC 8013\/3<\/td>\n<\/tr>\n

        <\/td>\n<\/td>\nOther subtypes<\/strong><\/td>\n<\/tr>\n
        <\/td>\n3<\/strong><\/td>\nCombined small cell carcinoma 8045\/3<\/td>\n<\/td>\n<\/tr>\n
        *<\/strong><\/td>\n<\/td>\nEC cell, serotonin-producing NET 8241\/3<\/td>\n<\/tr>\n
        *<\/strong><\/td>\n<\/td>\nEnterochromaffin-like cell tumor, malignant 8242\/3<\/td>\n<\/tr>\n
        *<\/strong><\/td>\n<\/td>\nGoblet cell carcinoid 8243\/3<\/td>\n<\/tr>\n
        *<\/strong><\/td>\n<\/td>\nMixed adenoneuroendocrine carcinoma 8244\/3<\/td>\n<\/tr>\n
        *<\/strong><\/td>\n<\/td>\nAdenocarcinoid tumor 8245\/3<\/td>\n<\/tr>\n
        *<\/strong><\/td>\n<\/td>\nNeuroendocrine carcinoma, NOS 8246\/3<\/td>\n<\/tr>\n
        *<\/strong><\/td>\n<\/td>\nNonfunctional pancreatic NET, G1, G2 8150\/3<\/td>\n<\/tr>\n
        *<\/strong><\/td>\n<\/td>\nInsulinoma 8151\/3<\/td>\n<\/tr>\n
        *<\/strong><\/td>\n<\/td>\nGlucagonoma 8152\/3<\/td>\n<\/tr>\n
        *<\/strong><\/td>\n<\/td>\nGastrin-producing NET (Gastrinoma) 8153\/3<\/td>\n<\/tr>\n
        *<\/strong><\/td>\n<\/td>\nMixed islet cell & exocrine adenocarcinoma 8154\/3<\/td>\n<\/tr>\n
        *<\/strong><\/td>\n<\/td>\nVIPoma 8155\/3<\/td>\n<\/tr>\n
        *<\/strong><\/td>\n<\/td>\nSomatostatin-producing NET 8156\/3<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
        *\u6d88\u5316\u9053\u795e\u7d93\u5167\u5206\u6ccc\u764c(\u5305\u542b\u7279\u6b8a\u7d44\u7e54\u578b\u614b)\u9700\u4f9d\u64damitotic count\u53ca\/\u6216ki-67 labeling index\u4f86\u5206\u7d1a\uff1a<\/h5>\n
        G1: mitotic count < 2 per 10 high power fields (HPF) AND < 3% Ki67 index;<\/h5>\n
        G2: mitotic count 2\u201320 per 10 HPF OR 3\u201320% Ki67 index;<\/h5>\n
        G3: mitotic count > 20 per 10 HPF OR > 20% Ki67 index<\/h5>\n

        [\u764c\u767b\u7b2c105001\u865f\u901a\u77e5\u6587\u5168\u6587\u4e0b\u8f09]<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

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